Publications
Recent highlights
2021
- Stealth Nanorods via the Aqueous Living Crystallisation-Driven Self-Assembly of Poly(2-Oxazoline)s
J. R. Finnegan, E. H. Pilkington, K. Alt, Md. A. Rahim, S. J. Kent, T. P. Davis, K. Kempe*,
Chem. Sci. 2021, Advance Article.
- Interactions of Core Cross-linked Poly(2-Oxazoline) and Poly(2-Oxazine) Micelles with Immune Cells in Human Blood
M. N. Leiske, M. Lai, T. Amarasena, T. P. Davis, K. J. Thurecht, S. J. Kent, K. Kempe*,
Biomaterials 2021, In press.
- Poly(2-ethyl-2-oxazoline) Bottlebrushes: How Nanomaterial Dimensions Can Influence Biological Interactions
D. Pizzi, A. M. Mahmoud, T. Klein, J. P. Morrow, J. Humphries, Z. H. Houston, N. L. Fletcher, C. A. Bell, K. J. Thurecht, K. Kempe*,
Eur. Polym. J. 2021, 151, 110447.
- Engineering Fluorescent Gold Nanoclusters Using Xanthate-Functionalized Hydrophilic Polymers: Toward Enhanced Monodispersity and Stability
V. G. Deepagan, M. N. Leiske, N. L. Fletcher, D. Rudd, T. Tieu, N. Kirkwood, K. J. Thurecht, K. Kempe*, N. H. Voelcker, A. Cifuentes-Rius
Nano Lett. 2021, 21, 476-484.
- Biodegradable Polymeric Nanoparticles For Brain-Targeted Drug Delivery
K. Kempe*, J. A. Nicolazzo,
Nanomedicines for Brain Drug Delivery 2021, 1-27.
2020
- Advances and Opportunities of Oil-in-oil Emulsions
A. Zia, E. Pentzer, S. Thickett, K. Kempe*,
ACS Appl. Mater. Interfaces 2020, 12, 38845-38861.
- Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A Structural-Activity Comparison of Biodistribution
J. Humphries, D. Pizzi, S. E. Sonderegger, N. L. Fletcher, Z. H. Houston, C. A. Bell, K. Kempe*, K. J. Thurecht
Biomacromolecules 2020, 21, 3318-3331.
- Tuning Cellular Interactions of Carboxylic Acid-Side-Chain-Containing Polyacrylates: The Role of Cyanine Dye Label and Side-Chain Type
A. M. Mahmoud, J. P. Morrow, D. Pizzi, A. M. Azizah, T. P. Davis, R. F. Tabor, K. Kempe*,
Biomacromolecules 2020, 21, 3007-3016.
- Dynamic solid-state ultrasound contrast agent for monitoring pH fluctuations in vivo
Julia A. Walker, K. Kempe*, Simon R. Corrie,
ACS Sens. 2020, 5, 1190-1197.
- The Evolving Landscape of Polymer Science and Engineering in Australia
K. Kempe*, Kristofer J. Thurecht.
Macromol. Rapid Commun. 2020, 41, 2000414.
- Next-generation polymeric nanomedicines for oncology: perspectives and future directions
Nicholas L. Fletcher, K. Kempe, Kristofer J. Thurecht.
Macromol. Rapid Commun. 2020, 41, 2000319.
- Synthesis of biscarboxylic acid functionalised EDTA mimicking polymers and their ability to form Zr (iv) chelation mediated nanostructures
Meike N. Leiske, Julia A. Walker, Aadarash Zia, Nicholas L. Fletcher, Kristofer J. Thurecht, T. P. Davis, K. Kempe*,
Polym. Chem. 2020, 11, 2799-2810.
- Nonionic Water-Soluble and Cytocompatible Poly(amide acrylate)s
A. M. Mahmoud, J. P. Morrow, D. Pizzi, S. Nanayakkara, T. P. Davis, K. Saito, K. Kempe*,
Macromolecules 2020, 53, 693-701.
- Cobalt-directed Assembly of Antibodies onto Metal-Phenolic Networks for Enhanced Particle Targeting
W. Zhang, Q. A. Besford, A. J. Christofferson, P. Charchar, J. J. Richardson, A. Elbourne, K. Kempe, C. Hagemeyer, M. R. Field, C. F. McConville,
I. Yarovsky, F. Caruso
Nano Lett. 2020, 20, 2660-2666.
- Poly(2-isopropenyl-2-oxazoline) - A structural Analogue to Poly(vinyl azlactone) with Orthogonal Reactivity
M. N. leiske, A. M. Mahmoud, N. M. Warne, J. A. C. M. Goos, S. Pascual, V. Montembault, L. Fontaine, T. P. Davis, M. R. Whittaker, K. Kempe*,
Polym. Chem. 2020, 11, 5681-5692.
2019
- Carboxylated Cy5-Labeled Comb Polymers Passively Diffuse the Cell Membrane and Target Mitochondria
A. M. Mahmoud, P. A. J. M. de Jongh, S. Briere, M. Chen, C. J. Nowell, A. P. R. Johnston, T. P. Davis, D. M. Haddleton, K. Kempe*,
ACS Appl. Mater. Interfaces 2019, 11, 31302-31310.
- Poly (2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures
D. Pizzi, J. Humphries, J. P. Morrow, N. L. Fletcher, C. A. Bell, K. J. Thurecht, K. Kempe*,
Eur. Polym. J. 2019, 121, 109258.
- A Sequential Native Chemical Ligation− Thiol-Michael Addition Strategy for Polymer-Polymer Ligation
A. Rajakanthan, P. A. J. M. de Jongh, J. S. Town, P. Wilson, K. Kempe*,
Polym. Chem. 2019, 10, 5242-5250.
- Revisiting cell–particle association in vitro: A quantitative method to compare particle performance
M. Faria, K. F. Noi, Q. Dai, M. Björnmalm, S. T. Johnston, K. Kempe, F. Caruso, E. J. Crampin,
J. Control. Rel. 2019, 307, 355-367.
- An optimised Cu (0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform
J. L. Grace, M. Amado, J. C. Reid, A. G. Elliott, C. Landersdorfer, N. Truong Phuoc, K. Kempe, M. A. Cooper, T. P. Davis, V. Montembault, S. Pascual, L. Fontaine, T. Velkov, J. F. Quinn, M. R. Whittaker,
J. Mater. Chem. B 2019, 7, 6796-6809.
- Functional brush poly(2-oxazine)s: Synthesis by CROP and RAFT, thermoresponsiveness and grafting onto IONPs
T. Klein, J. Parkin, P. A. J. M. de Jongh, L. Esser, T. Sepehrizadeh, G. Zheng, M. de Veer, K. Alt, C. E. Hagemeyer, D. M. Haddleton, T. P. Davis, M. Thelekkat, K. Kempe*,
Macromol. Rapid Commun. 2019, 1800911.
- Protein adsorption and coordination-based end-tethering of functional polymers on metal-phenolic network films
B. L. Tardy, J. J. Richardson, V. Nithipipat, K. Kempe, J. Guo, Y. Ju, K. L. Cho, M. A. Rahim, H. Ejima, F. Caruso,
Biomacromolecules 2019, 20, 1421-1428.
- Metal-dependent inhibition of amyloid fibril formation: synergistic effects of cobalt-tannic acid networks
W. Zhang, A. J. Christofferson, Q. A. Besford, J. J. Richardson, J. Guo, Y. Ju, K. Kempe, I. Yarovsky, F. Caruso,
Nanoscale 2019, 11, 1921-1928.
- In situ characterisation of protein corona formation on silica microparticles using confocal laser scanning microscopy combined with microfluidics
A. C. G. Weiss, K. Krueger, Q. A. Besford, M. Schlenk, K. Kempe, S. Foerster, F. Caruso,
ACS Appl. Mater. Interfaces 2019, 11, 2459-2469.
2018
- Importance of thermally induced aggregation on 19F Magnetic Resonance Imaging of perfluoropolyether-based comb-shaped poly(2-oxazoline)s
C. Zhang, R. J. P. Sanchez, C. Fu, R. Clayden-Zabik, H. Peng, K. Kempe*, A. K. Whittaker,
Biomacromolecules 2018, 20, 365-374.
- Spontaneous zwitterionic copolymerisation: an undervalued and efficacious technique for the synthesis of functional degradable oligomers and polymers
P. A. J. M. de Jongh, D. M. Haddleton, K. Kempe*,
Prog. Polym Sci. 2018, 87, 228-246.
- Overcoming the Blood-Brain Barrier: The role of nanomaterials in treating neurological diseases
D. Furtado, M. Bjoernmalm, S. Ayton, A. I. Bush, K. Kempe*, F. Caruso,
Adv. Mat. 2018, 30, 1801362.
- Human plasma proteome association and cytotoxicity of nano-graphene oxide grafted with stealth polyethylene glycol and poly(2-ethyl-2-oxazoline)
M. Wang, O. J. R. Gustafsson, G. Siddiqui, I. Javed, H. G. Kelly, T. Blin, H. Yin, S. J. Kent, D. J. Creek, K. Kempe*, P. C. Ke, T. P. Davis,
Nanoscale 2018, 10, 10863-10875.
- Functional hydrophobic and hetero-grafted block comb polymers via a combination of spontaneous zwitterionic copolymerisation and redox-initiated RAFT polymerisation
A. M. Mahmoud, A. Rajakanthan, K. Kempe*,
Polym. Chem. 2018, 9, 1562-1566.
- Unraveling the Spontaneous Zwitterionic Copolymerization Mechanism of Cyclic Imino Ethers and Acrylic Acid
J. Steinkoenig, P. A. J. M. de Jongh, D. M. Haddleton, A. S. Goldmann, C. Barner-Kowollik, K. Kempe*,
Macromolecules 2018, 51, 318-327.
- Microfluidic examination of the "hard" biomolecular corona formed on engineered particles in different biological milieu
A. C. G. Weiss, K. Kempe, S. Foerster, F. Caruso,
Biomacromolecules 2018, 19, 2580-2594.
- Tumor targeting with pH-responsive poly(2-oxazoline)-based nanogels for metronomic doxorubicin treatment
D. Hoelzer, M. N. Leiske, M. Hartlieb, T. Bus, D. Pretzel, S. Hoeppener, K. Kempe, R. Thierbach, U. S. Schubert,
Oncotarget 2018, 9, 22316-22331.
- Rethinking the impact of the protonable amine density on cationic polymers for gene delivery:
A comparative study of partially hydrolyzed Poly(2-ethyl-2-oxazoline) and linear poly(ethylene imine)s
M. Bauer, L. Tauhardt, H. M. L. Lambermont-Thijs, K. Kempe, R. Hoogenboom, U. S. Schubert, D. Fischer,
Eur. J. Pharm. Biopharm. 2018, 133, 112-121.
2017
- Specific and differential binding of N-acetylgalactosamine glycopolymers to MGL and ASGPR
J. Tanaka, A. Gleinich, Q. Zhang, R. Whitfield, K. Kempe, D. M. Haddleton, T. P. Davis, D. A. Mitchell, S. Perrier, P. Wilson,
Biomacromolecules 2017, 18, 1624-1633. - Hydrolyzable Poly[Poly(Ethylene Glycol) Methyl Ether Acrylate]–Colistin Prodrugs through Copper-Mediated Photoinduced Living Radical Polymerization
C. Zhu, E. K. Schneider, V. Nikolaou, T. Klein, J. Li, T. P. Davis, M. R. Whittaker, P. Wilson, K. Kempe, T. Velkov, D. M. Haddleton,
Bioconjugate Chem. 2017, 28, 1916-1924. - Thiol-reactive (co)polymers scaffolds comprising organic arsenical acrylamides
C. Footman, P. A. J. M. de Jongh, J. Tanaka, R. Peltier, K. Kempe, T. P. Davis, P. Wilson,
Chem. Commun. 2017, 53, 8447-8450.
- Chain and step growth polymerizations of cyclic imino ethers: from Poly(2-oxazoline)s to Poly(esteramide)s
K. Kempe*
Macromol. Chem Phys. 2017, DOI: 10.1002/macp.201700021 (invited Talent article).
- Engineered hydrogen-bonded glycopolymer capsules and their interactions with antigen presenting cells
K. Kempe*, S. D. Xiang, P. Wilson, Md. A. Rahim, Y. Ju, M. R. Whittaker, D. M. Haddleton, M. Plebanski, F. Caruso, T. P. Davis,
ACS Appl. Mater. Interfaces 2017, 9, 6444-6452.
- A traceless reversible polymeric colistin prodrug to combat multidrug-resistant (MDR) Gram-negative bacteria
C. Zhu, E. K. Schneider, J. Wang, K. Kempe, P. Wilson, T. Velkov, J. Li, T. P. Davis, M. R. Whittaker, D. M. Haddleton,
J. Control. Release 2017, 259, 83-91. - Tailoring the cellular uptake and fluorescence of poly(2-oxazoline) based nanogels
M. Hartlieb, T. Bus, J. Kuebel, D. Pretzel, S. Hoeppener, M. Leiske, K. Kempe, B. Dietzek, U. S. Schubert,
Bioconjugate Chem. 2017, 28, 1229-1235.
- Poly(2-oxazoline)-based micro- and nanoparticles: A review
P. Wilson, P.-C. Ke, T. P. Davis, K. Kempe*,
Eur. Polym. J. 2017, 88, 486-515 (invited contribution to special issue ’50 years poly(2-oxazoline)s’).
- Thermal study on polyester networks based on the renewable monomers citric acid and gluconolactone
P. A. J. M. de Jongh, P. Prem, E. Khoshdel, P. Wilson, K. Kempe, D. M. Haddleton,
Polym. Int. 2017, 66, 59-63. - A hydrogel based localized release of colistin for antimicrobial treatment of burn wound infections
C. Zhu, Z. Jinxin, K. Kempe, P. Wilson, J. Wang, T. Velkov, J. Li, T. P. Davis, M. R. Whittaker, D. M. Haddleton,
Macromol. Biosci. 2017, 17, DOI: 10.1002/mabi.201600320.
2016
- Facile one-pot/one-step synthesis of heterotelechelic N-acylated poly(aminoester) macromonomers for carboxylic acid decorated comb polymers
P. A. J. M. de Jongh, Mechelle Bennett, Greg S. Sulley, P. Wilson, T. P. Davis, D. M. Haddleton, K. Kempe*,
Polym. Chem. 2016, 7, 6703-6707.
- Comb poly(oligo(2-ethyl-2-oxazoline)methacrylate-peptide conjugates prepared by aqueous Cu(0) mediated living radical polymerization.
J. Collins, S. J. Wallis, A. Simula, M. R. Whittaker, P. Wilson, T. P. Davis, D. M. Haddleton, K. Kempe*,
Macromol. Rapid Commun. 2016, DOI: 10.1002/marc.201600534.
- Dopamine-terminated multifunctional polymers to give fluorescent magnetic nanoparticles for efficient cellular uptake and biomedical imaging
Q. Zhang, G. Nurumbetov, A. Simula, C. Zhu, M. Li, P. Wilson, K. Kempe, B. Yang, L. Tao, D. M. Haddleton,
Polym. Chem. 2016, 7, 7002-7010. - Well-defined PDMAEA stars via Cu(0)-mediated reversible deactivation radical polymerisation
R. Whitfield, A. Anastasaki, N. P. Truong, P. Wilson, K. Kempe, J. A. Burns, T. P. Davis, D. M. Haddleton,
Macromolecules 2016, 49, 8914-8924. - Metal-Phenolic Supramolecular Gelation
Md. A. Rahim, M. Bjoernmalm, T. Suma, M. Faria, Y. Ju, K. Kempe, M. Muellner, H. Ejima, A. D. Stickland, F. Caruso,
Angew. Chem. Int. Ed. 2016, 55, 13803-13807.
- Dual stimuli-responsive comb polymers from modular N-acylated poly(aminoester) based macromonomers
P. A. J. M. de Jongh, A. Mortiboy, G. S. Sully, Mechelle Bennett, Athina Anastasaki, P. Wilson, D. M. Haddleton, K. Kempe*,
ACS Macro Lett. 2016, 5, 321-325.
- Facile carbohydrate-mimetic modifications of poly(ethylene imine) carriers for gene delivery applications
C. Englert, M. Fevre, R. J. Wojtecki, W. Cheng, Q. Xu, C. Yang, X. Ke, M. Hartlieb, K. Kempe, J. M. Garcia, R. J. Ono, U. S. Schubert, Y. Y. Yang, J. L. Hedrick,
Polym. Chem. 2016, 7, 5862-5872. - Stability enhancing N-terminal PEGylation of oxytocin exploiting different polymer architectures and conjugation approaches
J. Collins, K. Kempe, P. Wilson, C. A. Blindauer, M. P. McIntosh, T. P. Davis, M. R. Whittaker, D. M. Haddleton,
Biomacromolecules 2016, 17, 2755-2766. - Reversible regulation of stimuli responsive property of dithiomaleimide-containing copolymers via sequential thiol exchange reactions
Z. Tang, P. Wilson, K. Kempe, H. Chen, D. M. Haddleton,
ACS Macro Lett. 2016, 5, 709-713. - Polyurea microcapsules from isocyanatoethyl methacrylate copolymers
N. Risangud, T. R. Congdon, D. J. Keddie, P. Wilson, K. Kempe, D. M. Haddleton,
J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 2698-2705. - Controlled aqueous polymerization of acrylamides and acrylates and ‘in-situ’ depolymerisation in the presence of dissolved CO2
D. J. Lloyd, V. Nikolaou, J. Collins, C. Waldron, A. Anastasaki, S. P. Bassett, S. M. Howdle, A. Blanazs, P. Wilson, K. Kempe, D. M. Haddleton,
Chem. Commun. 2016, 52, 6533-6536. - Polymerisation of 2-acrylamido-2-methylpropane sulfonic acid sodium salt (NaAMPS) and acryloyl phosphatidylcholine (APC) via aqueous Cu(0)-mediated radical polymerisation
V. Nikolaou, A. Simula, M. Droesbeke, N. Risangud, A. Anastasaki, K. Kempe, P. Wilson, D. M. Haddleton,
Polym. Chem. 2016, 7, 2452-2456. - Shape-dependent activation of cytokine secretion by polymer capsules in human monocyte-derived macrophages
X. Chen, Y. Yan, M. Muellner, Y. Ping, J. Cui, K. Kempe, C. Cortez-Jugo, F. Caruso,
Biomacromolecules 2016, 17, 1205-1212. - Preparation of non-spherical particles from amphiphilic block copolymers
K. Kempe, R. A. Wylie, M. Dimitriou, H. Tran, R. Hoogenboom, U. S. Schubert, C. J. Hawker, L. M. Campos, L. A. Connal,
J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 750-757. - Cu(0)-mediated living radical polymerization; a versatile tool for materials synthesis
A. Anastasaki, V. Nikolaou, G. Nurumbetov, P. Wilson, K. Kempe, J. F. Quinn, T. P. Davis, M. R. Whittaker, D. M. Haddleton,
Chem. Rev. 2016, 116, 835-877.
2015
- Novel comb polymers from alternating N-acylated poly(aminoester)s obtained by spontaneous zwitterionic copolymerisation
K. Kempe*, P. A. J. M. de Jongh, A. Anastasaki, P. Wilson, D. M. Haddleton,
Chem. Commun. 2015, 51, 16213-16216.
- Enhancing the biocompatibility and biodegradability of linear poly(ethylene imine) through controlled oxidation
C. Englert, M. Hartlieb, P. Bellstedt, K. Kempe, C. Yuang, S. K. Chu, X. Ke, J. M. Garcia, R. J. Ono, M. Fevre, R. J. Wojtecki, U. S. Schubert, Y. Y. Yang, J. L. Hedrick,
Macromolecules 2015, 48, 7420-7427. - Surface confined amorphous films from metal coordinated sub-nm phenolic ligands
Md. A. Rahim, K. Kempe, M. Muellner, H. Ejima, Y. Ju, K. L. Cho, M. P. van Koeverden, T. Suma, J. Braunger, M. Leeming, B. Abrahams, F. Caruso,
Chem. Mater. 2015, 27, 5825-5832. - Investigating the mechanism of copper(0)-mediated living radical polymerization in aqueous media
F. Alsubaie, A. Anastasaki, V. Nikolaou, A. Simula, G. Nurumbetov, P. Wilson, K. Kempe, D. M. Haddleton,
Macromolecules 2015, 48, 6421-6432. - Investigating the mechanism of copper(0)-mediated living radical polymerization in organic media
F. Alsubaie, A. Anastasaki, V. Nikolaou, A. Simula, G. Nurumbetov, P. Wilson, K. Kempe, D. M. Haddleton,
Macromolecules 2015, 48, 5517-5525. - Well-defined protein/peptide-polymer conjugates by aqueous Cu-LRP: synthesis and controlled self-assembly
Q. Zhang, M. Li, C. Zhu, G. Nurumbetov, Z. Li, P. Wilson, K. Kempe, D. M. Haddleton,
J. Am. Chem. Soc. 2015, 137, 9344-9353. - Single-chain antibody-targeted, thrombin-sensitive polymer capsules for the treatment of acute thrombosis
S. T. Gunawan, K. Kempe, T. Bonnard, J. Cui, K. Alt, X. Wang, L. S. Law, G. K. Such, K. Peter, C. E. Hagemeyer, F. Caruso,
Adv. Mat. 2015, 27, 5153-5157. - Capsosomes as long-term delivery vehicles for protein therapeutics
J. W. Maina, J. J. Richardson, R. Chandrawati, K. Kempe, M. P. van Koeverden, F. Caruso,
Langmuir 2015, 31, 7776-7781. - Organic arsenicals as efficient and highly specific linkers for protein/peptide-polymer conjugation
P. Wilson, A. Anastasaki, M. R. Owen, K. Kempe, D. M. Haddleton, S. K. Mann, A. P. R. Johnston, J. F. Quinn, M. R. Whittaker,
P. J. Hogg, T. P. Davis,
J. Am. Chem. Soc. 2015, 137, 4215-4222. - Water soluble triblock and pentablock poly(methacryloyl nucleosides) from copper-mediated living radical polymerization using PEG macroinitiators
M. Garcia, M. P. Beecham, K. Kempe, D. M. Haddleton, A. Khan, A. Marsh,
Eur. Polym. J. 2015, 66, 444-451. - In-situ conjugation of dithiophenol maleimide polymers and oxytocin for stable and reversible polymer-peptide conjugates
J. Collins, J. Tanaka, P. Wilson, K. Kempe, T. P. Davis, M. P. McIntosh, M. R. Whittaker, D. M. Haddleton,
Bioconjugate Chem. 2015, 26, 633-638. - Photo-induced synthesis of α,ω-telechelic sequence-controlled multiblock copolymers
A. Anastasaki, V. Nikolaou, N. W. McCaul, A. Simula, J. Godfrey, C. Waldron, P. Wilson, K. Kempe, D. M. Haddleton,
Macromolecules 2015, 48, 1404-1411. - Monoclonal antibody-functionalized polymer particles: Targeting cancer cells in the presence of protein coronas
Q. Dai, Y. Yan, C.-S. Ang, K. Kempe, M. M. J. Kamphuis, S. Dodds, F. Caruso,
ACS Nano 2015, 9, 2876-2885. - Unprecedented control over acrylate and acrylamide polymerization in aqueous and organic media
A. Anastasaki, V. Nikolaou, F. Alsubaie, A. Simula, C. Waldron, D. J. Lloyd, J. Godfrey, G. Nurumbetov, Q. Zhang, P. Wilson,
K. Kempe, D. M. Haddleton,
ACS Symp. Ser., 2015, 118, 29-45. - Rapid synthesis of well-defined α,ω-telechelic multiblock copolymers in aqueous medium: in situ generation of functional diols
A. Simula, V. Nikolaou, A. Anastasaki, G. Nurumbetov, P. Wilson, K. Kempe, D. M. Haddleton,
Polym. Chem. 2015, 6, 2226-2233. - Core cross-linked micelles and vesicles based on the self-assembly of double hydrophilic poly(2-oxazoline) block copolymers as potential drug carriers
M. Hartlieb, D. Pretzel, M. Wagner, S. Hoeppener, P. Bellstedt, M. Görlach, C. Englert, K. Kempe, U. S. Schubert,
J. Mat. Chem. B 2015, 3, 1748-1759. - Photo-induced living radical polymerization of acrylates utilizing a discrete copper(II)/formate complex
A. Anastasaki, V. Nikolaou, F. Brandford-Adams, G. Nurumbetov, Q. Zhang, G. J. Clarkson, D. J. Fox, P. Wilson, K. Kempe, D. M. Haddleton,
Chem. Commun. 2015, 51, 5626-5629. - Templated polymerizations on solid supports mediated by complementary nucleoside interactions
M. Garcia, K. Kempe, D. M. Haddleton, A. Khan, A. Marsh,
Polym. Chem. 2015, 6, 1944-1951. - Hydrosilylation as an efficient tool for polymer synthesis and modification with methacrylates
N. Risangud, Z. Li, A. Anastasaki, P. Wilson, K. Kempe, D. M. Haddleton,
RSC Adv. 2015, 5, 5879-5885. - Covalently cross-linked poly(2-oxazoline) materials for biomedical applications - from hydrogels to self-assembled and templated structures
M. Hartlieb, K. Kempe, U. S. Schubert,
J. Mat. Chem. B 2015, 3, 526-538. - A cationic poly(2-oxazoline) with high in vitro transfection efficiency identified by a library approach
A. Rinkenauer, L. Tauhardt, F. Wendler, K. Kempe, M. Gottschaldt, A. Schallon, U. S. Schubert,
Macromol. Biosci. 2015, 15, 414-425. - Stabilization of Factor VIII by poly(2-oxazoline) hydrogels
M. Hartlieb, S. Schubert, K. Kempe, N. Windhab, U. S. Schubert,
J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 10-14.
2014
- Intracellular degradable hydrogen bonded polymer capsules
K. Kempe, S. L. Ng, S. T. Gunawan, K. F. Noi, F. Caruso,
Adv. Funct. Mat. 2014, 24, 6187-6194. - Fundamental studies of hybrid poly(2-diisopropylamino)ethyl methacrylate)/ poly(N-vinyl pyrrolidone) films and capsules
S. L. Ng, J. P. Best, K. Kempe, K. Liang, A. P. R. Johnston, G. K. Such, F. Caruso,
Biomacromolecules 2014, 15, 2784-2792. - Dextran-graft-linear poly(ethylene imine)s for gene delivery: Influence of linking strategies on physiochemical and biological properties
S. Ochrimenko, A. Vollrath, L. Tauhardt, K. Kempe, S. Schubert, U. S. Schubert, D. Fischer,
Carbohyd. Polym. 2014, 113, 597-606. - Semi-automated multi-dimensional characterization of synthetic copolymers
S. Crotty, A. Baumgaertel, N. Fritz, E. Altuntas, K. Kempe, C. Weber, U. S. Schubert,
Eur. Polym. J. 2014, 60, 153-162. - Dual stabilized nanoengineered polymer capsules with gated permeability
K. Kempe, K. F. Noi, S. L. Ng, M. Müllner, F. Caruso,
Polymer 2014, 55, 6451-6459. - Tuning biodegradation of polymer-peptide blend replica particles
S. T. Gunawan, K. Kempe, G. K. Such, J. Cui, K. Liang, J. J. Richardson, A. P. R. Johnston, F. Caruso,
Biomacromolecules 2014, 15, 4429-4438. - Emerging methods for the fabrication of polymer capsules
J. Cui, M. P. van Koeverden, M. Muellner, K. Kempe, F. Caruso,
Adv. Colloid Interface Sci. 2014, 207, 14-31. - Coordination-driven multistep assembly of metal-polyphenol films and capsules
Md. A. Rahim, H. Ejima, K. L. Cho, K. Kempe, M. Müllner, J. P. Best, F. Caruso,
Chem. Mater. 2014, 26, 1645-1653. - Linear poly(ethylene imine)-based hydrogels for effective binding and release of DNA
C. Englert, L. Tauhardt, M. Hartlieb, K. Kempe, M. Gottschaldt, U. S. Schubert,
Biomacromolecules 2014, 15, 1124-1131. - Matrix supported poly(2-oxazoline)-based hydrogels for DNA catch and release
M. Hartlieb, D. Pretzel, C. Englert, K. Kempe, M. Gottschaldt, U. S. Schubert,
Biomacromolecules 2014, 15, 1970-1978. - Zwitterionic poly(2-oxazoline)s as promising candidates for blood contacting applications
L. Tauhardt, D. Pretzel, K. Kempe, M. Gottschaldt, D. Pohlers, U. S. Schubert,
Polym. Chem. 2014, 5, 5751-5764. - Synthesis and in vitro activity of platinum containing 2-oxazoline-based glycopolymers
L. Tauhardt, D. Pretzel, S. Bode, J. Czaplewska, K. Kempe, M. Gottschaldt, U. S. Schubert,
J. Polym. Sci., Part A: Polym. Chem. 2014, 52, 2703-2714. - Amine end-functionalized poly(2-ethyl-2-oxazoline) as promising coating material for antifouling applications
L. Tauhardt, M. Frant, D. Pretzel, M. Hartlieb, C. Bücher, G. Hildebrand, B. Schröter, C. Weber, K. Kempe, M. Gottschaldt, K. Liefeith, U. S. Schubert,
J. Mat. Chem. B 2014, 2, 4883-4893.
2013
- Tuning the morphology of triblock terpoly(2-oxazoline)s containing a 2-phenyl-2-oxazoline block with varying fluorine content
U. Mansfeld, S. Hoeppener, K. Kempe, J.-F. Gohy, U. S. Schubert,
Soft Matter 2013, 9, 5966-5974. - Parallel high-throughput screening of polymer vectors for non-viral gene delivery: Evaluation of structure-property-relationships of transfection
A. C. Rinkenauer, A. Vollrath, A. Schallon, L. Tauhardt, K. Kempe, S. Schubert, D. Fischer, U. S. Schubert,
ACS Comb. Sci. 2013, 15, 475-482. - Poly(2-oxazoline) functionalized surfaces: from modification to application
L. Tauhardt, K. Kempe, M. Gottschaldt, U. S. Schubert,
Chem. Soc. Rev. 2013, 42, 7998-8011. - Strongly phase-segregating block copolymers with sub-20 nm features
K. Kempe, K. L. Killops, J. E. Poelma, H. Jung, J. Bang, R. Hoogenboom, H. Tran, C. J. Hawker, U. S. Schubert, L. M. Campos,
ACS Macro Lett. 2013, 2, 677-682. - Poly(2-oxazoline) hydrogels for controlled fibroblast attachment
B. Farrugia, K. Kempe, U. S. Schubert, R. Hoogenboom, T. R. Dargaville,
Biomacromolecules 2013, 14, 2724-2732. - Immersive polymer assembly on immobilized particles for automated capsule preparation
J. J. Richardson, K. Liang, K. Kempe, H. Ejima, J. Cui, F. Caruso,
Adv. Mater. 2013, 25, 6874-6878. - Clickable poly(2-oxazoline) architectures for the fabrication of low-fouling polymer capsules
K. Kempe, S. L. Ng, K. F. Noi, M. Müllner, S. T. Gunawan, F. Caruso,
ACS Macro Lett. 2013, 2, 1069-1072. - A strong cationic Bronsted acid, [H(OEt2)2][Al{OC(CF3)3}4], as an efficient initiator for the cationic ring-opening polymerization of 2-alkyl-2-oxazolines
T. Rudolph, K. Kempe, S. Crotty, R. M. Paulus, U. S. Schubert, I. Krossing, F. H. Schacher,
Polym. Chem. 2013, 4, 495-505. - In vitro hemocompatibility and cytotoxicity study of poly(2-methyl-2-oxazoline) for biomedical applications
M. Bauer, S. Schroeder, L. Tauhardt, K. Kempe, U. S. Schubert, D. Fischer,
J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 1816-1821. - A systematic investigation of the effect of side chain branching on the glass transition temperature and the mechanical properties of aliphatic (co-)poly(2-oxazoline)s
K. Kempe, E. Rettler, R. Paulus, A. Kuse, R. Hoogenboom, U. S. Schubert,
Polymer 2013, 54, 2036-2042. - Cationic poly(2-oxazoline) hydrogels for reversible DNA binding
M. Hartlieb, David Pretzel, K. Kempe, C. Fritzsche, R. Paulus, M. Gottschaldt, U. S. Schubert,
Soft Matter 2013, 9, 4693-4704. - pH degradable dendron-functionalized poly(2-ethyl-2-oxazoline) prepared by a cascade "double-click" reaction
K. Kempe, S. Onbulak, U. S. Schubert, A. Sanyal, R. Hoogenboom,
Polym. Chem. 2013, 4, 3236-3244. - Comparison of ESI, APCI and MALDI for the (tandem) mass analysis of poly(2-ethyl-2-oxazoline)s with various end groups
E. Altuntas, C. Weber, K. Kempe, U. S. Schubert,
Eur. Polym. J. 2013, 49, 2172-2185.
2012
- Poly(2-ethyl-2-oxazoline) as alternative for polyethylene glycol – comparison of in vitro cytotoxicity and hemocompatibility
M. Bauer, C. Lautenschlaeger, K. Kempe, L. Tauhardt, D. Fischer, U. S. Schubert,
Macromol. Biosci. 2012, 12, 986-998. - Poly(2-oxazoline) hydrogel monoliths via thiol-ene coupling
T. R. Dargaville, R. Forster, B. L. Farrugia, K. Kempe, L. Voorhaar, U. S. Schubert, R. Hoogenboom,
Macromol. Rapid Commun. 2012, 33, 1695-1700. - Toward the design of LPEI containing block copolymers: Improved synthesis protocol, selective hydrolysis, and detailed characterization
L. Tauhardt, K. Kempe, U. S. Schubert,
J. Polym. Sci., Part A: Polym. Chem. 2012, 50, 4516-4523. - Star-shaped block copolymers by copper-catalyzed azide-alkyne cycloaddition for potential drug delivery applications
C. v. d. Ehe, K. Kempe, M. Bauer, A. Baumgaertel, M. Hager, D. Fischer, U. S. Schubert,
Macromol. Chem. Phys. 2012, 213, 2146-2156. - Side-chain modification and grafting onto via olefin cross-metathesis
L. Montero de Espinosa, K. Kempe, U. S. Schubert, R. Hoogenboom, M. A. R. Meier,
Macromol. Rapid Commun. 2012, 33, 2023-2028. - Molar mass, chemical-composition, and functionality-type distributions of poly(2-oxazoline)s revealed by a variety of separation techniques
A. Chojnacka, K. Kempe, H. C. van de Ven, C. Englert, R. Hoogenboom, U. S. Schubert, H.-G. Janssen, P. Schoenmakers,
J. Chromatogr. A 2012, 1265, 123-132. - Clicking on/with polymers: a rapidly expanding field for the straightforward preparation of novel macromolecular architectures
K. Kempe, A. Krieg, C. R. Becer, U. S. Schubert,
Chem. Soc. Rev. 2012, 41, 176-191. - Self-assembling chiral block copolymers – from spherical micelles to fibers
M. M. Bloksma, S. Hoeppener, C. D’Haese, K. Kempe, U. Mansfeld, J.-F. Gohy, U. S. Schubert, R. Hoogenboom,
Soft Matter 2012, 8, 165-172. - 2-Iso-propenyl-2-oxazoline: a versatile monomer for the functionalization of polymers obtained via RAFT
C. Weber, T. Neuwirth, K. Kempe, B. Oezkahraman, E. Tamahkar, C. R. Becer, U. S. Schubert,
Macromolecules 2012, 45, 20-27. - Tandem mass spectrometry of poly(ethylene imine)s: a comparison study between electrospray ionization (ESI) and matrix assisted laser desorption/ionization (MALDI)
E. Altuntas, K. Knop, L. Tauhardt, K. Kempe, A. Crecelius, M. Jaeger, M. Hager, U. S. Schubert,
J. Mass Spectrom. 2012, 47, 105-114.
2011
- Linear poly(ethylene imine) – optimized synthesis and characterization on the way to “pharmagrade” batches
L. Tauhardt, K. Kempe, K. Knop, E. Altuntas, M. Jaeger, S. Schubert, D. Fischer, U. S. Schubert,
Macromol. Chem. Phys. 2011, 212, 1918-1924. - Microwave-assisted polymerizations: recent status and future perspectives
K. Kempe, C. R. Becer, U. S. Schubert,
Macromolecules 2011, 44, 5825-5842. - A green approach for the synthesis and thiol-ene modification of alkene functionalized poly(2-oxazoline)s
K. Kempe, R. Hoogenboom, U. S. Schubert,
Macromol. Rapid Commun. 2011, 32, 1484-1489. - Threefold metal-free efficient reactions onto a multifunctional poly(2-oxazoline) scaffold
K. Kempe, R. Hoogenboom, M. Jaeger, U. S. Schubert,
Macromolecules 2011, 44, 6424-6432. - In-situ synthesis of cyclopentadienyl endcapped poly(2-ethyl-2-oxazoline) and subsequent ambient temperature Diels-Alder conjugations
M. Glassner,# K. Kempe,# R. Hoogenboom, U. S. Schubert, C. Barner-Kowollik,
Chem. Commun. 2011, 47, 10620-10622. - Characterization of poly(2-oxazoline) homo- and copolymers by liquid chromatography at critical conditions
A. Baumgaertel, C. Weber, N. Fritz, G. Festag, E. Altuntas, K. Kempe, U. S. Schubert,
J. Chromatogr. A 2011, 1218, 8370-8378. - Poly(2-oxazoline) glycopolymers with tunable LCST behavior
K. Kempe, T. Neuwirth, J. Czaplewska, M. Gottschaldt, R. Hoogenboom, U. S. Schubert,
Polym. Chem. 2011, 2, 1737-1743. - Responsive glyco-poly(2-oxazoline)s: synthesis, cloud point tuning and lectin binding
K. Kempe, C. Weber, K. Babiuch, M. Gottschaldt, R. Hoogenboom, U. S. Schubert,
Biomacromolecules 2011, 12, 2591-2600. - Analysis of different synthetic homopolymers by the use of a new calculation software for tandem MS spectra
A. Baumgaertel, K. Scheubert, B. Pietsch, K. Kempe, A. Crecelius, S. Boecker, U. S. Schubert,
Rapid Commun. Mass Spectrom. 2011, 25, 1765-1778.
2010
- Rational design of an amorphous poly(2-oxazoline) with a low glass-transition temperature: monomer synthesis, copolymerization, and properties
K. Kempe, S. Jacobs, H. M. L. Lambermont-Thijs, M. M. W. M. Fijten, R. Hoogenboom, U. S. Schubert,
Macromolecules 2010, 43, 4098-4104. - Multifunctional poly(2-oxazoline) nanoparticles for biological applications
K. Kempe, A. Vollrath, H. W. Schaefer, T. G. Poehlmann, C. Biskup, R. Hoogenboom, S. Hornig, U. S. Schubert,
Macromol. Rapid Commun. 2010, 31, 1869-1873. - Discovering new block terpolymer micellar morphologies
K. Kempe, R. Hoogenboom, S. Hoeppener, C. A. Fustin, J. F. Gohy, U. S. Schubert,
Chem. Commun. 2010, 46, 6455-6457. - Design of new amphiphilic triblock copoly(2-oxazoline)s containing a fluorinated segment
K. Kempe, A. Baumgaertel, R. Hoogenboom, U. S. Schubert,
J. Polym. Sci., Part A: Polym. Chem. 2010, 48, 5100-5108. - ESI-MS & MS/MS analysis of poly(2-oxazoline)s with different side groups
E. Altuntas, K. Kempe, A. Crecelius, R. Hoogenboom, U. S. Schubert,
Macromol. Chem. Phys. 2010, 211, 2312-2322. - Characterization of different poly(2-oxazoline) block copolymers by MALDI-TOF MS/MS and ESI-Q-TOF MS/MS
A. Baumgaertel, E. Altuntas, K. Kempe, A. Crecelius, U. S. Schubert,
J. Polym. Sci., Part A: Polym. Chem. 2010, 48, 5533-5540.
2009
- Screening the synthesis of 2-substituted-2-oxazolines
K. Kempe, M. Lobert, R. Hoogenboom, U. S. Schubert,
J. Comb. Chem. 2009, 11, 274-280. - Synthesis and characterization of a series of diverse poly(2-oxazoline)s
K. Kempe, M. Lobert, R. Hoogenboom, U. S. Schubert,
J. Polym. Sci., Part A: Polym. Chem. 2009, 47, 3829-3838.
2007
- Diethyl 2,2'-(ethylenediimino)di-(cyclopentenecarboxylate)
H. Goerls, J. Notni, K. Kempe, E. Anders,
Acta Crystallogr E 2007, 63, O4095-U3469.
2006
- Zinc thiolate complexes [ZnLn(SR)](+) with azamacrocyclic ligands, part II: Mechanism of the reaction with CS2
J. Notni, S. Schenk, A. Roth, W. Plass, H. Gorls, U. Uhlemann, A. Walter, M. Schmitt, J. Popp, S. Chatzipapadopoulos, T. Emmler, H. Breitzke, J. Leppert, G. Buntkowsky, K. Kempe, E. Anders,
Eur. J. Inorg. Chem. 2006, 2783-2791.